Cell Wall and Secreted Proteins of Candida albicans : Identification, Function, and Expression
نویسندگان
چکیده
منابع مشابه
Cell wall and secreted proteins of Candida albicans: identification, function, and expression.
The cell wall is essential to nearly every aspect of the biology and pathogenicity of Candida albicans. Although it was initially considered an almost inert cellular structure that protected the protoplast against osmotic offense, more recent studies have demonstrated that it is a dynamic organelle. The major components of the cell wall are glucan and chitin, which are associated with structura...
متن کاملCandida albicans cell wall proteins.
The Candida albicans cell wall maintains the structural integrity of the organism in addition to providing a physical contact interface with the environment. The major components of the cell wall are fibrillar polysaccharides and proteins. The proteins of the cell wall are the focus of this review. Three classes of proteins are present in the candidal cell wall. One group of proteins attach to ...
متن کاملSecreted proteins of Candida albicans.
The predicted secretome of the opportunistic fungal pathogen Candida albicans contains more than 200 ORFs of diverse and often unknown function. Majority of the secreted proteins that have been experimentally evaluated to date are hydrolytic enzymes (proteinases, phospholipases and lipases). Acting on the interface between the pathogen and the host, the secreted hydrolases may enable invasion o...
متن کاملComparison of cell wall proteins in putative Candida albicans & Candida dubliniensis by using modified staining method & SDSPAGE
Background: Candida species are among the most common causes of opportunistic fungal diseases. Among Candida species, Candida albicans is responsible for most infections. Having many strains, C. albicans is very polymorph. C. dubliniensis is very similar to albicans species both morphologically and physiologically. For an infection to occur, cell wall proteins play an important role as they en...
متن کاملCandida albicans Structural and Secreted Proteins Modulate CD4/CD8 Ratio in Tumor Infiltrating Lymphocytes of Spontaneous Adenocarcinoma Bearing Mice
Background: Candida albicans is one of the most important opportunistic pathogens that suppress immunologic mechanisms of the host. It is speculated that structural and secretory proteins of C. albicans have immunomodulatory effects in cancer. Objective: To evaluate the effects of C. albicans structural and secreted proteins on intratumoral CD4/CD8 ratio as well as the survival rate in BALB/c t...
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ژورنال
عنوان ژورنال: Microbiology and Molecular Biology Reviews
سال: 1998
ISSN: 1092-2172,1098-5557
DOI: 10.1128/mmbr.62.1.130-180.1998